Detalhe da pesquisa
1.
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Am J Hum Genet
; 110(2): 284-299, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693378
2.
Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits.
Am J Hum Genet
; 109(1): 66-80, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995504
3.
Genetic effects on liver chromatin accessibility identify disease regulatory variants.
Am J Hum Genet
; 108(7): 1169-1189, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038741
4.
Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits.
Genome Res
; 31(12): 2258-2275, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815310
5.
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci.
PLoS Genet
; 17(10): e1009865, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699533
6.
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.
PLoS Genet
; 16(9): e1009019, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915782
7.
Enhancer deletion and allelic effects define a regulatory molecular mechanism at the VLDLR cholesterol GWAS locus.
Hum Mol Genet
; 28(6): 888-895, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445632
8.
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.
Am J Hum Genet
; 102(4): 620-635, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625024
9.
Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.
PLoS Genet
; 14(4): e1007275, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29621232
10.
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes.
Proc Natl Acad Sci U S A
; 114(9): 2301-2306, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193859
11.
Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.
Am J Hum Genet
; 98(2): 229-42, 2016 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26805783
12.
Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol.
Am J Hum Genet
; 97(6): 801-15, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26637976
13.
Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.
PLoS Genet
; 10(9): e1004633, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211022
14.
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.
Hum Mol Genet
; 23(4): 1108-19, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24105470
15.
Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles.
Genomics
; 104(2): 105-12, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997396
16.
Liver regulatory mechanisms of noncoding variants at lipid and metabolic trait loci.
HGG Adv
; 5(2): 100275, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297830
17.
Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.
Diabetes
; 72(11): 1707-1718, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37647564
18.
Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
bioRxiv
; 2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961277
19.
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
Nat Genet
; 55(6): 973-983, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37291194
20.
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.
Nat Commun
; 11(1): 4912, 2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32999275